‘Grey’s Anatomy’ Season 19: Everything We Know About Ellen Pompeo, Cast Shakeups and More

Grey’s Anatomy is gearing up for a new chapter, but season 19 is going to look dramatically different.

With ABC’s long-running medical drama nearing two decades on television and surpassing 400 episodes, there’s bound to be changes in front and behind the camera. As series star Ellen Pompeo formally steps back for the upcoming season, with plans to only appear in eight episodes (though she’ll continue to narrate), Grey’s favorites and franchise newcomers will be stepping into the spotlight.